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(1S)-2-chloro-1-[(2S)-6-fluoro-3,4-dihydro-2H-chromen-2-yl]ethanol

(1S)-2-chloro-1-[(2S)-6-fluoro-3,4-dihydro-2H-chromen-2-yl]ethanol

CAS: 1315508-96-3

Molecular Formula: C11H12ClFO2

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(1S)-2-chloro-1-[(2S)-6-fluoro-3,4-dihydro-2H-chromen-2-yl]ethanol - Names and Identifiers

Name (1S)-2-chloro-1-[(2S)-6-fluoro-3,4-dihydro-2H-chromen-2-yl]ethanol
Synonyms (1S)-2-chloro-1-[(2S)-6-fluoro-3,4-dihydro-2H-chromen-2-yl]ethanol
2H-1-Benzopyran-2-methanol, α-(chloromethyl)-6-fluoro-3,4-dihydro-, (αS,2S)-
CAS 1315508-96-3
EINECS 807-024-8

(1S)-2-chloro-1-[(2S)-6-fluoro-3,4-dihydro-2H-chromen-2-yl]ethanol - Physico-chemical Properties

Molecular FormulaC11H12ClFO2
Molar Mass230.66
Density1.310±0.06 g/cm3(Predicted)
Boling Point351.6±37.0 °C(Predicted)
pKa13.85±0.20(Predicted)

(1S)-2-chloro-1-[(2S)-6-fluoro-3,4-dihydro-2H-chromen-2-yl]ethanol - Introduction

Nebivolol impurity 43(NAB-43) is a chemical material that belongs to the impurity class of compounds. Here is more information about NAB-43:

Nature:
NAB-43 is a colorless or yellowish Crystal, molecular formula C10H10BrN3O3, chemical name is 2-amino -1-(2-bromoethyl) benzamide. It is a solid at room temperature and soluble in some organic solvents, such as ethanol and dimethylformamide.

Use:
NAB-43 is a commonly used intermediate compound in the pharmaceutical field and can be used to synthesize other chemicals, such as drugs and pesticides. It can be used as a catalyst for some organic synthesis reactions, or for the preparation of potential drug candidate compounds.

Preparation Method:
Regarding the preparation method of NAB-43, specific experimental details may be subject to patent protection or trade secrets. Generally speaking, it can be synthesized by performing chemical reactions on the corresponding lead compounds or key steps in the synthetic route. The synthetic process may include a reaction of the Tigris reagent, a substitution reaction, or a carboxyacylation reaction.

Safety Information:
For the safe use of NAB-43, it is necessary to follow the safe practice of chemical laboratories. It can be eye and skin irritant, so wear appropriate personal protective equipment such as lab gloves and goggles when handling. During use or storage, it is necessary to avoid contact with oxidants, strong acids and strong bases to prevent dangerous reactions.

In short, nebivolol impurity 43 is a commonly used chemical intermediate compound that can be used to synthesize drugs and chemicals, but it needs to follow relevant safety practices when used.
Last Update:2024-04-09 21:54:55
(1S)-2-chloro-1-[(2S)-6-fluoro-3,4-dihydro-2H-chromen-2-yl]ethanol
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